It’s 2am in Tel Aviv, Beirut and Gaza. Here’s a recap of the latest developments:

• At least one blast was reported and smoke seen over Beirut’s southern suburbs in the early hours of Saturday, as the Israeli military issued new alerts for residents of the Burj al-Barajneh and Choueifat neighbourhoods to immediately evacuate. The Israeli military launched a series of strikes on southern Beirut on Thursday night, in one of the most intense bombardments on the city since the campaign began last week. A source close to Hezbollah told the AFP news agency that Israel had conducted 11 consecutive strikes on the group’s stronghold in the Lebanese capital. Hashem Safieddine, the most likely candidate to replace Hassan Nasrallah as leader of Hezbollah, was the target of the strikes, according to reports. The result of the attacks, said to have targeted a meeting of senior Hezbollah figures, is unclear. The Israeli military also ordered people in 20 more southern towns in Lebanon to evacuate immediately as it presses ahead with its incursions.

• More than 2,000 people have been killed in Lebanon in nearly a year of fighting between Israel and Hezbollah, according to figures by the Lebanese government on Wednesday. Most have been killed in the past two weeks, when cross-border fighting turned into a wide-ranging Israeli assault. A spokesperson for the UN’s secretary general said the toll on civilians in Lebanon from Israel’s campaign against Hezbollah is “totally unacceptable”.

• At least four hospitals in Lebanon announced the suspension of work amid the ongoing Israeli bombardment. Lebanon’s prime minister, Najib Mikati, urged the international community to pressure Israel “to allow rescue and relief teams to reach bombed sites and allow them to move” casualties. On Thursday, the head of the World Health Organization said 28 health workers in Lebanon have been killed in the space of 24 hours.

• Israel cut off a key road near to Lebanon’s Masnaa border crossing with Syria that has been used by hundreds of thousands of people to flee Israeli bombardments in recent days. Israel has accused Hezbollah of using border crossings with Syria to bring in weapons and amid evidence that Israel is targeting key roads, both international routes and internally, as it did during the 2006 war. More than 300,000 people – a vast majority of them Syrian – have crossed from Lebanon into Syria over the past 10 days to escape escalating Israeli bombardment, according to Lebanon’s government.

• The northern regions of Israel were targeted by Hezbollah rockets almost continuously throughout Friday. The Israel Defense Forces said Hezbollah had launched about 100 rockets into Israel on Friday. Hezbollah said fighters had targeted “an Israeli enemy troop force during its advance” towards an area west of the border village of Yarun “with artillery shells and a rocket salvo”, and it claimed responsibility for a series of attacks on Israeli soldiers across the border earlier in the day.

• Joe Biden, the US president, urged Israel against striking Iran’s oil facilities. Biden told reporters on Friday that Israel is “not going to make a decision immediately” on how to retaliate against Iran’s missile attacks earlier this week, but that “If I were in their shoes, I’d be thinking about other alternatives than striking oilfields.”

• Iran’s supreme leader, Ayatollah Ali Khamenei, vowed that Hezbollah in Lebanon and Hamas in Gaza will re-emerge strongly with new leaders. In a rare public sermon in front of tens of thousands in Tehran on Friday, Khamenei defended the “legal and legitimate” ballistic missile attack on Israel this week that Iran has said was in retaliation for the deaths of the Hezbollah secretary general, Hassan Nasrallah, and the Hamas political leader, Ismail Haniyeh.

• Iran’s foreign minister, Abbas Araghchi, visited Beirut on Friday to meet Lebanon’s caretaker prime minister, Najib Mikati, and speaker of parliament, Nabih Berri – a close ally of Hezbollah. “Be sure that the Islamic Republic of Iran is and will be firmly standing by the friends in Lebanon,” Araghchi told reporters, adding that if Israel carries out another attack on Iran, Tehran will retaliate in a harsh way.

• At least 29 Palestinians have been killed in Israeli military strikes across the Gaza Strip on Friday, according to medics. Israeli attacks continued across Gaza on Friday, including in the city of Deir al-Balah, where an Israeli strike on a home has killed at least four people, according to the Palestinian news agency Wafa. The military also launched bombs that ignited fires in homes in the Nuseirat refugee camp, while Israeli warplanes struck several sites in the southern city of Khan Younis, “resulting in further casualties and injuries”, Wafa reported.

• Gaza’s health ministry said at least 41,802 people have been killed and 96,844 injured in Israeli military attacks on Gaza since last October in its latest update on Friday. The ministry has said thousands are most likely lost in the rubble. Much of the Palestinian territory’s infrastructure has been destroyed by Israeli strikes, as well as its health facilities and schools.

• Israeli soldiers conducted widespread raids in the Hebron province in the occupied West Bank on Friday morning, resulting in the detention of more than 24 people, including “minors”, the Palestinian news agency reported. The majority of those detained were reportedly taken from the town of Beit Ummar. Human rights groups and international organisations have alleged widespread abuse of inmates detained by Israel in raids in the occupied West Bank.

• Funerals were held on Friday for some of the 18 people killed in the occupied West Bank in an Israeli airstrike on a refugee camp in Tulkarm. Among the dead, according to Palestinan reports, was a family of four including two children. A spokesperson for the Palestinian Authority president, Mahmoud Abbas, described the attack as a “heinous crime” and a “massacre”. The attack was condemned by the UN rights office. Hamas’ armed wing, the al–Qassam Brigades, confirmed that one of its commanders, Zahi Yaser Abd al-Razeq Oufi, and seven other fighters were killed in the Israeli strike.

• US forces carried out strikes on 15 targets in areas of Yemen controlled by the Houthi rebels on Friday, the US military confirmed. The media in Yemen reported a new round of airstrikes, including on the capital, Sana’a, and near the airport at the port of Hodeidah, and Israeli strikes continued in Gaza and Lebanon. The strikes were targeted at weapons systems, bases and other equipment belonging to the Iran-backed group, US officials said. The Guardian understands that that there was no UK involvement in the airstrikes on Friday.

• The last UK-government chartered flight for British nationals to leave Lebanon will depart from Beirut on Sunday. More than 250 British nationals have left Lebanon on flights chartered by government, the UK Foreign Office said on Friday. There are no more scheduled flights “due to a decrease in demand” although this will be kept under “constant” review, it said. Many countries around the world are working to organise flights out of Lebanon so that its citizens can escape the escalating conflict there.

At least one blast has been reported and smoke seen over Beirut’s southern suburb, Reuters is reporting.

It comes shortly after the Israeli military issued evacuation orders for civilians in a specific building in the Burj al Barajneh neighbourhood of the Lebanese capital.

The Israel Defense Forces (IDF) has also issued a new evacuation order just minutes ago for a specific building, warning people to stay away from the area by more than 500 metres.

The Israeli military has issued new evacuation orders for residents of Beirut’s southern suburbs ahead of expected Israeli airstrikes on the Lebanese capital.

Avichay Adraee, a spokesperson for the Israel Defense Forces, posted a map showing a specific area and ordering civilians to leave the area.

We reported earlier that three Lebanese hospitals announced the suspension of work amid the ongoing Israeli bombardment. That figure has gone up to four, according to AFP.

The grounds of the Salah Ghandour hospital in Bint Jbeil in south Lebanon were “subject to Israeli artillery shelling”, Lebanese national news agency NNA reported.

Mohammed Sleiman, director of the Islamic Health Committee-run facility, told the news agecny that seven medical personnel were wounded when the hospital was struck “directly”, adding that the facility was evacuated.

Mais al-Jabal hospital in south Lebanon on the border with Israel announced “the halt to work of all departments”, the news agency reported, citing factors including “enemy targeting of the hospital” since last October and problems for supply lines and staff access.

Sainte Therese hospital, on the edge of Beirut’s southern suburbs, said it suffered “huge damage” after “Israeli warplanes’ target[ed] the vicinity” of the facility on Thursday which “led to the halt of hospital services”.

The head of the Marjayoun government hospital, Mounes Kalakesh, told multiple news outlets that an Israeli airstrike “targeted ambulances at the main entrance to the hospital”. Five paramedics were killed and seven were wounded, he said.

The UN’s humanitarian coordinator in Lebanon has released an additional $2m from the Lebanon humanitarian fund to help address the deteriorating situation, a spokesperson for the UN chief said.

Stéphane Dujarric, spokesperson for the UN secretary general António Guterres, said the latest funds came in addition to $10m already released from the Lebanon fund, and $10m from the UN’s main central emergency response fund.

In a separate statement, he said the toll on civilians in Lebanon from Israel’s campaign against Hezbollah is “totally unacceptable”, adding:

All parties must do whatever they can at all times to protect civilians and civilian infrastructure and ensure that civilians are never put in harm’s way.

Turkey’s president, Recep Tayyip Erdoğan, has accused Israel of “shamelessly” attacking the UN’s secretary general, António Guterres.

Israel’s foreign minister, Israel Katz, said on Wednesday that he was barring Guterres from entering the country, accusing the UN chief of failing to specifically condemn Iran’s missile attack on the country this week.

Katz called Guterres an “anti-Israel secretary-general who lends support to terrorists, rapists, and murderers” and declared him persona non grata.

Guterres pointedly condemned Iran’s attack at a UN security council meeting on Wednesday. The security council has expressed its full support to the UN secretary general.

On Friday, Erdoğan said Israel “is shamelessly challenging” Guterres and that “196 countries in the world will stand by the UN secretary-general”.